The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2022
Filed:
Dec. 02, 2016
Applicant:
Seattle Genetics, Inc., Bothell, WA (US);
Inventors:
Patrick J. Burke, Seattle, WA (US);
Joel Courter, Lynnwood, WA (US);
Assignee:
SEAGEN INC., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 47/68 (2017.01); C07K 5/02 (2006.01); A61K 47/65 (2017.01); A61K 47/64 (2017.01); A61P 35/02 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/454 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/551 (2017.08); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 31/454 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61K 47/6811 (2017.08); A61K 47/6817 (2017.08); A61K 47/6849 (2017.08); A61K 47/6883 (2017.08); A61K 47/6889 (2017.08); A61P 35/02 (2018.01); C07K 5/021 (2013.01); A61K 38/00 (2013.01);
Abstract
Compounds and compositions are disclosed in which a quaternized drug unit is linked to a targeting ligand unit from which a tertiary amine-containing drug is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease using the compounds and compositions of the invention are also disclosed.