The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2022
Filed:
Oct. 22, 2018
Applicant:
Omrix Biopharmaceuticals Ltd., Rehovot, IL;
Inventors:
Yair Pilpel, Rehovot, IL;
Sivan Doron, Moshav Arugot, IL;
Yuri Zherdev, Rehovot, IL;
Tamara Byk-Tennenbaum, Kiryat Ono, IL;
Assignee:
Omrix Biopharmaceuticals Ltd., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C12N 9/74 (2006.01); C12N 15/115 (2010.01); A61K 38/36 (2006.01); A61K 47/26 (2006.01); A61M 5/19 (2006.01); C12N 15/113 (2010.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
A61K 38/4833 (2013.01); A61K 38/363 (2013.01); A61K 47/26 (2013.01); A61M 5/19 (2013.01); C12N 9/6429 (2013.01); C12N 15/113 (2013.01); C12N 15/115 (2013.01); C12Y 304/21005 (2013.01); G01N 33/5308 (2013.01); C12N 2310/113 (2013.01); G01N 2333/974 (2013.01);
Abstract
The present invention is directed to compounds, methods for stabilizing thrombin activity with a thrombin binding oligonucleotide and to stabilized thrombin. The thrombin binding oligonucleotide is capable of inhibiting thrombin activity whereby the inhibition can be reversed with an antisense oligonucleotide.