The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2022
Filed:
Aug. 14, 2020
Applicant:
Mirum Pharmaceuticals, Inc., Foster City, CA (US);
Inventors:
Thomas Jaecklin, Delemont, CH;
Alejandro Dorenbaum, Mill Valley, CA (US);
Assignee:
MIRUM PHARMACEUTICALS, INC., Foster City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4995 (2006.01); A61P 1/16 (2006.01); A61P 17/04 (2006.01); A61K 31/554 (2006.01); A61K 31/7042 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4995 (2013.01); A61K 31/554 (2013.01); A61K 31/7042 (2013.01); A61P 1/16 (2018.01); A61P 17/04 (2018.01);
Abstract
Provided herein are methods for treating cholestasis in a subject having a liver disease. The method includes administering to the subject an Apical Sodium-dependent Bile Acid Transporter (ASBTI). More specifically, the present invention relates to methods for treating cholestasis in a subject where the method includes administering an ASBTI to a subject at a dose of at least 10 μg/kg/day.