The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 25, 2022

Filed:

Dec. 19, 2018
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Vsevolod Polotsky, Pikesville, MD (US);

Honggang Cui, Lutherville, MD (US);

Roxana Elena Mitrut, Plainsboro, NJ (US);

Mi-kyung Shin, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); A61K 47/55 (2017.01); A61K 47/64 (2017.01); A61K 47/54 (2017.01); A61P 9/12 (2006.01); A61K 9/06 (2006.01); A61K 9/70 (2006.01); A61K 31/05 (2006.01); A61K 31/122 (2006.01); A61K 31/131 (2006.01); A61K 31/133 (2006.01); A61K 31/155 (2006.01); A61K 31/352 (2006.01); A61K 31/405 (2006.01); A61K 31/4174 (2006.01); A61K 31/4184 (2006.01); A61K 31/428 (2006.01); A61K 31/444 (2006.01); A61K 31/4709 (2006.01); A61K 31/506 (2006.01); A61K 31/69 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 9/06 (2013.01); A61K 9/70 (2013.01); A61K 31/05 (2013.01); A61K 31/122 (2013.01); A61K 31/131 (2013.01); A61K 31/133 (2013.01); A61K 31/155 (2013.01); A61K 31/352 (2013.01); A61K 31/405 (2013.01); A61K 31/4174 (2013.01); A61K 31/4184 (2013.01); A61K 31/428 (2013.01); A61K 31/444 (2013.01); A61K 31/4709 (2013.01); A61K 31/506 (2013.01); A61K 31/69 (2013.01); A61K 47/54 (2017.08); A61K 47/55 (2017.08); A61K 47/64 (2017.08); A61P 9/12 (2018.01);
Abstract

The present invention provides compositions and methods for treating hypertension and obstructive sleep apnea utilizing hydrogel compositions comprising drug amphiphiles with TRPM 7 antagonists for use in a subject, including use on the carotid body of a subject.


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