The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2022

Filed:

Apr. 26, 2017
Applicant:

Qu Biologies Inc., Burnaby, CA;

Inventors:

Harold David Gunn, Vancouver, CA;

David W. Mullins, Norwich, VT (US);

Shirin Kalyan, Burnaby, CA;

Momir Bosiljcic, Burnaby, CA;

Monan Angela Zhang, Burnaby, CA;

Mark Bazett, Burnaby, CA;

Marcel Thalen, Burnaby, CA;

Dermot McGovern, Los Angeles, CA (US);

Boyko Traychev Kabakchiev, Guelph, CA;

Ho Pan Sham, Burnaby, CA;

Assignee:

Qu Biologics Inc., Burnaby, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12Q 1/6883 (2018.01); A61K 39/108 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G01N 33/6863 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6866 (2013.01); G01N 33/6869 (2013.01); A61K 39/0258 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01);
Abstract

The invention provides therapeutic compositions that present an artificial repertoire of mammalian pattern recognition receptor (PRR) agonists, so that the pattern of PRR agonists recapitulates a distinct portion of a PRR agonist signature of a mammalian pathogen. The artificial repertoire of PRR agonists may be formulated together in a therapeutic vehicle for combined presentation to an innate immune cell resident in a target tissue in a mammalian host, and the vehicle adapted to deliver the PRR agonists to the target tissue, so as to modulate an immune response.


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