The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2022
Filed:
Sep. 07, 2018
Applicant:
Bavarian Nordic A/s, Kvistgaard, DK;
Inventor:
Robin Steigerwald, Munich, DE;
Assignee:
Bavarian Nordic A/S, Kvistgaard, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/863 (2006.01); C12N 15/861 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8636 (2013.01); C12N 15/86 (2013.01); C12N 15/8613 (2013.01); C12N 2710/24121 (2013.01); C12N 2710/24134 (2013.01); C12N 2710/24141 (2013.01); C12N 2710/24143 (2013.01); C12N 2710/24151 (2013.01); C12N 2740/11022 (2013.01); C12N 2760/14122 (2013.01); C12N 2799/02 (2013.01); C12N 2800/22 (2013.01);
Abstract
The invention relates to vectors comprising two or more homologous nucleotide sequences and methods for generating them. The invention concerns substituting bases in the homologous nucleotide sequences with different bases that do not alter the encoded amino acid sequence. The invention allows for the reduction of intramolecular recombination between homologous nucleotide sequences, in particular in mammalian cells. The invention further relates to nucleotide sequences containing substituted bases.