The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2022
Filed:
Oct. 11, 2019
Applicant:
Washington University, St. Louis, MO (US);
Inventors:
Timothy M. Miller, St. Louis, MO (US);
Mariah Lawler Hoye, St. Louis, MO (US);
Ted Hyman, St. Louis, MO (US);
Erica Koval, St. Louis, MO (US);
Joseph Dougherty, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/7105 (2006.01); C12Q 1/6883 (2018.01); C12N 15/113 (2010.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/7105 (2013.01); A61P 25/28 (2018.01); C12N 15/111 (2013.01); C12Q 1/6883 (2013.01); C12N 2310/141 (2013.01); C12N 2320/10 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/178 (2013.01);
Abstract
The present invention relates to compositions and methods for detecting motor neuron-specific miRNAs in a population of cells or subject. More particularly, the invention relates to detecting motor neuron-specific miRNAs to detect and treat motor neuron diseases associated with dysregulation of motor neuron-specific miRNAs, such as Amyotrophic Lateral Sclerosis (ALS).