The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2022

Filed:

Dec. 17, 2018
Applicant:

Boehringer Ingelheim Vetmedica Gmbh, Ingelheim am Rhein, DE;

Inventors:

Matthias Eckhardt, Biberach an der Riss, DE;

Monika Brink, Gau-Algesheim, DE;

Frank Himmelsbach, Mittelbiberach, DE;

Stefan Sahli, Zofingen, CH;

Chutian Shu, Pudong District, CN;

Xiao-Jun Wang, Ridgefield, CT (US);

Beat Theodor Weber, Zofingen, CH;

Bing-Shiou Yang, Southbury, CT (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/00 (2006.01); C07C 69/614 (2006.01); C07C 291/00 (2006.01); C07H 7/04 (2006.01);
U.S. Cl.
CPC ...
C07H 1/00 (2013.01); C07C 69/614 (2013.01); C07C 291/00 (2013.01); C07H 7/04 (2013.01); C07C 2601/16 (2017.05);
Abstract

The invention relates to a process for the manufacture of the crystalline compound according to formula (I) comprising the steps (a) deacetylating the final intermediate (FI), (b) forming the crystalline compound according to formula (I) by reacting the deacetylated final intermediate of step (a) with L-proline and water and isolating the final reaction product; processes of manufacturing intermediates thereof; process intermediates and their uses in the processes according to the present invention.


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