The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2022

Filed:

Apr. 23, 2020
Applicants:

Risen (Suzhou) Pharma Tech Co., Ltd., Jiangsu, CN;

Shanghai Junshi Biosciences Co., Ltd., Shanghai, CN;

Inventors:

Jiasheng Lu, Shanghai, CN;

Jiamin Gu, Suzhou, CN;

Gang Chen, Suzhou, CN;

Xiaolin Zhang, Suzhou, CN;

Feng Zhou, Suzhou, CN;

Xianqi Kong, Dollard des-Ormeaux, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6574 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07F 9/22 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65744 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07F 9/222 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01);
Abstract

There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for inhibition or modulation of the activity of cyclin dependent kinases (CDK) and/or glycogen synthase kinase-3 (GSK-3), for the treatment of disease states or conditions mediated by cyclin dependent kinases and/or glycogen synthase kinase-3, including cancers.


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