The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2022
Filed:
Aug. 12, 2020
Applicant:
United Therapeutics Corporation, Silver Spring, MD (US);
Inventors:
Hitesh Batra, Herndon, VA (US);
Sudersan M. Tuladhar, Silver Spring, MD (US);
David A. Walsh, Spotsylvania, VA (US);
Assignee:
United Therapeutics Corporation, Silver Spring, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 67/343 (2006.01); C07C 45/67 (2006.01); C07C 45/81 (2006.01); C07C 67/31 (2006.01); C07C 67/333 (2006.01); C07C 45/64 (2006.01); C07C 45/78 (2006.01);
U.S. Cl.
CPC ...
C07C 67/343 (2013.01); C07C 45/64 (2013.01); C07C 45/67 (2013.01); C07C 45/78 (2013.01); C07C 45/81 (2013.01); C07C 67/31 (2013.01); C07C 67/333 (2013.01); C07C 2603/14 (2017.05);
Abstract
The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin. The methods include heating the compound of Formula 2 at a temperature of 180° C. to 185° C. Wherein the heating comprises irradiating the compound of formula 2 with microwave radiation.