The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2022

Filed:

Mar. 14, 2019
Applicant:

Kryptos Biotechnologies, Inc., Hayward, CA (US);

Inventors:

Jun Ho Son, Albany, CA (US);

Sewoon Han, Albany, CA (US);

Jinyong Lee, Emeryville, CA (US);

Assignee:

Kryptos Biotechnologies, Inc., Hayward, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 7/00 (2006.01); B01L 9/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/567 (2013.01); B01L 7/52 (2013.01); B01L 7/525 (2013.01); B01L 7/54 (2013.01); B01L 9/527 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/10 (2013.01); B01L 2300/044 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/123 (2013.01); B01L 2300/168 (2013.01); B01L 2300/18 (2013.01); B01L 2400/06 (2013.01);
Abstract

Systems and methods for light based heating of light absorbing sources for modification of nucleic acids through fast thermal cycling of polymerase chain reaction are provided. The system includes a polymeric fluidic device comprising one or more reaction wells. A first light absorbing material is disposed on a first support to define a reaction well and first and second ports are coupled to the reaction wells. The first and second ports are configured to allow input of a fluidic sample into the reaction well. A lyophilized reagent is pre-loaded in the reaction well. A light source is configured to illuminate the first light absorbing material. A first portion of light illuminated onto the first light absorbing material is absorbed into the first light absorbing material and is configured to elevate the temperature of the first light absorbing material to heat the fluidic sample within the reaction well.


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