The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2022
Filed:
Jan. 05, 2017
Applicant:
Ascendis Pharma Growth Disorders A/s, Hellerup, DK;
Inventors:
Kennett Sprogøe, Holte, DK;
Harald Rau, Dossenheim, DE;
Ana Bernhard, Heidelberg, DE;
Ulrich Hersel, Heidelberg, DE;
Felix Cleenmann, Mainz, DE;
Thomas Wegge, Heidelberg, DE;
Assignee:
ASCENDIS PHARMA GROWTH DISORDERS A/S, Hellerup, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 47/60 (2017.01); A61P 43/00 (2006.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 38/22 (2013.01); A61P 43/00 (2018.01);
Abstract
The present invention relates to controlled-release CNP agonists having an at least 5-fold longer degradation half-life in an in vitro NEP degradation assay than the corresponding released CNP agonist, to pharmaceutical compositions comprising said controlled-release CNP agonist, their use and to methods of treatment.