The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2022

Filed:

Jun. 07, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Liangfang Zhang, San Diego, CA (US);

Che-Ming Jack Hu, Novato, CA (US);

Ronnie H. Fang, San Diego, CA (US);

Brian T. Luk, San Diego, CA (US);

Soracha Kun Thamphiwatana, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/337 (2006.01); A61K 31/7042 (2006.01); A61K 47/69 (2017.01); A61P 31/04 (2006.01); A61K 9/50 (2006.01); A61K 45/06 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/51 (2013.01); A61K 9/5068 (2013.01); A61K 9/5084 (2013.01); A61K 9/5094 (2013.01); A61K 31/337 (2013.01); A61K 31/7042 (2013.01); A61K 45/06 (2013.01); A61K 47/6901 (2017.08); A61P 31/04 (2018.01); A61K 2300/00 (2013.01); B82Y 5/00 (2013.01);
Abstract

The present invention relates to prevention and/or treatment of infection by a platelet-targeting microbe in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating (and/or related uses) infection by a platelet-targeting microbe in a subject, using, inter alia, an effective amount of a nanoparticle comprising a) an inner core comprising a non-cellular material, b) an outer surface comprising a cellular membrane derived from a platelet; and optionally c) an agent for preventing said infection, treating said infection, diagnosing said infection, prognosing said infection and/or monitoring prevention or treatment of said infection. Exemplary platelet-targeting infections include infections by a bacterium, a virus, a fungus and/or a parasite.


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