The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 18, 2022

Filed:

Mar. 11, 2020
Applicants:

Blossom Innovations, Llc, Waltham, MA (US);

The General Hospital, Boston, MA (US);

Inventors:

Richard Rox Anderson, Boston, MA (US);

Jayant Bhawalkar, Auburndale, MA (US);

Dieter Manstein, Coral Gables, FL (US);

Joseph Ting, Acton, MA (US);

Vincent Zuo, Boston, MA (US);

Lilit Garibyan, Brookline, MA (US);

Kachiu Lee, Wynnewood, PA (US);

Oge Onwudiwe, Silver Spring, MD (US);

William A. Farinelli, Danvers, MA (US);

Assignees:

Blossom Innovations, LLC, Waltham, MA (US);

The General Hospital Corporation, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 18/20 (2006.01); A61B 5/00 (2006.01); A61B 17/54 (2006.01); A61M 37/00 (2006.01); A61K 45/06 (2006.01); A61M 11/00 (2006.01); A61M 3/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/449 (2013.01); A61B 5/0066 (2013.01); A61B 5/0068 (2013.01); A61B 5/0071 (2013.01); A61B 5/4839 (2013.01); A61B 17/54 (2013.01); A61K 45/06 (2013.01); A61M 37/0092 (2013.01); A61M 3/00 (2013.01); A61M 11/00 (2013.01); A61M 2037/0007 (2013.01); A61M 2205/36 (2013.01);
Abstract

A treatment system can include a channel generation system configured to expose an infected region of a target tissue with a laser beam traveling along an optical axis and focused at a focal volume located in or adjacent to the target tissue. The laser beam can have a wavelength ranging from about 100 nm to about 400 nm. The laser beam can be configured to generate at least a first channel in the infected region. The treatment system can also include a detection system configured to detect a first radiation generated by one or more of (i) the target tissue, (ii) a fungi coupled to the infected region in the target tissue, and (iii) an adjacent tissue located proximal to the target tissue as a result of interaction with the laser beam. The treatment system can also include a delivery system configured to deposit an active treatment agent in the at least first channel.


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