The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Apr. 09, 2019
Applicant:
Cellectis, Paris, FR;
Inventors:
Philippe Duchateau, Draveil, FR;
Julien Valton, New York, NY (US);
Assignee:
CELLECTIS, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 15/85 (2006.01); C07K 14/47 (2006.01); C12N 9/22 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C07K 14/47 (2013.01); C12N 9/22 (2013.01); C12N 15/85 (2013.01); G01N 33/5308 (2013.01); C07K 2319/61 (2013.01); C07K 2319/80 (2013.01);
Abstract
The present invention relates to polypeptides and more particularly to Transcription Activator-Like Effector derived proteins that allow to efficiently target and/or process nucleic acids. Particularly, the present invention reports the characterization of TALE derived proteins that can efficiently target methylated DNA. The present invention more specifically relates to TALE derived proteins that allow activation of methylated promoters responsible for gene silencing.