The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Apr. 13, 2018
Amolifescience Co., Ltd., Seoul, KR;
Kollodis Biosciences, Inc., North Augusta, SC (US);
Chan Kim, Gwangju, KR;
Kyuwon Baek, Seoul, KR;
Hui-Gwan Goo, Seoul, KR;
Sangjae Lee, Seoul, KR;
Bongjin Hong, Pohang-si, KR;
Song Hee Koo, Seoul, KR;
In Yong Seo, Seoul, KR;
Seung Hoon Lee, Paju-si, KR;
Ji Hyun Lee, Incheon, KR;
Seonho Jang, Seoul, KR;
Dong-Sik Seo, Incheon, KR;
Amolifescience Co., Ltd., Seoul, KR;
Kollodis BioSciences, Inc., North Augusta, SC (US);
Abstract
Described is a three-dimensional (3D) microenvironment presenting defined biochemical and physical cues that regulate cellular behavior and use of the microenvironment. A composition to form the 3D microenvironment is provided by combining one or more natural or synthetic polymeric materials and substrate proteins recombinantly or chemically functionalized with a variety of bioactive peptides such as extracellular matrix-derived or growth factor-derived peptides. Also described are devices and methods for screening for optimal combinations of the bioactive motifs in order to create an extracellular microenvironment that can regulate specific cellular behavior such as cell growth, proliferation, migration or differentiation.