The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Jan. 29, 2021
Novo Nordisk A/s, Bagsvaerd, DK;
Karina Thorn, Farum, DK;
Bjarne Gram Hansen, Alleroed, DK;
Laust Bruun Johnsen, Skodsborg, DK;
Mikkel Nors Harndahl, Roskilde, DK;
Zhiru Yang, Beijing, CN;
Henrik Oestergaard, Oelstykke, DK;
Per J. Greisen, Belmont, MA (US);
Eva Johansson, Vaerloese, DK;
Morten Groenbech Rasch, Smoerum, DK;
Jianhe Chen, Beijing, CN;
Anders Svensson, Malmoe, SE;
Haisun Zhu, Norfolk, MA (US);
Rong Zhou, Beijing, CN;
Prafull S. Gandhi, Ballerup, DK;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The present invention relates to multispecific procoagulant antibodies capable of binding to coagulation Factor IX (FIX) and/or the activated form thereof Factor IXa (FIXa), and Factor X (FX) and/or the activated form thereof Factor Xa (FXa) and promoting FX activation by FIXa, antibodies binding their epitopes or parts thereof and methods and composition for treating subjects suffering from a coagulopathy such as haemophilia A as well as kits, methods of manufacture and methods of use.