The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Sep. 23, 2020
Applicant:
Xintrum Pharmaceuticals, Ltd., Jiangsu, CN;
Inventors:
Wenchao Liu, Nanjing, CN;
Hongliang Sun, Nanjing, CN;
Yi Zhang, Nanjing, CN;
Yuesheng Wang, Nanjing, CN;
Assignee:
XINTRUM PHARMACEUTICALS, LTD., Nanjing, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/00 (2006.01); C07K 1/20 (2006.01); C12N 5/071 (2010.01); C07K 14/48 (2006.01);
U.S. Cl.
CPC ...
C07K 1/20 (2013.01); C12N 5/0682 (2013.01); C07K 14/48 (2013.01);
Abstract
A method for removing precursors in recombinant human nerve growth factor (rhNGF) by hydrophobic interaction chromatography (HIC) is provided, where a Chinese hamster ovary (CHO) cell culture is processed by column chromatography for preliminary purification, and the pretreated sample obtained therefrom is further processed in a HIC column by washing the sample and then eluting the HIC column.