The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Sep. 13, 2017
Janssen Pharmaceutica NV, Beerse, BE;
Patrick Rene Angibaud, Saint Pierre d'Autils, FR;
Vineet Pande, Vosselaar, BE;
Barbara Herkert, Flonheim, DE;
Daniel Jason Krosky, Blue Bell, PA (US);
Olivier Alexis Georges Querolle, Saint Vigor, FR;
Aaron Nathaniel Patrick, Doylestown, PA (US);
Isabelle Noelle Constance Pilatte, Louviers, FR;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to compounds of formula (I): wherein the variables have the meaning defined in the Specification. The compounds according to the present invention are useful for therapy and/or prophylaxis in a mammal, and in particular to spiro bicyclic compounds, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.