The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Mar. 26, 2018
Applicant:
Caldan Therapeutics Limited, Edinburgh, GB;
Inventors:
Jane Brown, Nottingham, GB;
Stephen Connolly, York, GB;
Steffen V. F. Hansen, Copenhagen, DK;
Gavin Milne, Nottingham, GB;
Bharat Shimpukade, Bangalore, IN;
Don Smyth, Nottingham, GB;
Gerard Thomas, Nottingham, GB;
Trond Ulven, Copenhagen, DK;
Matjaz Brvar, Zagorje ob Savi, SI;
Aaron Rigby, Nottingham, GB;
Assignee:
CALDAN THERAPEUTICS LTD, Edinburgh, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/04 (2006.01); C07D 401/04 (2006.01); C07D 405/04 (2006.01); A61K 31/47 (2006.01); A61K 31/4725 (2006.01); A61P 3/10 (2006.01); C07D 223/16 (2006.01);
U.S. Cl.
CPC ...
C07D 223/16 (2013.01); A61P 3/10 (2018.01); C07D 217/04 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01);
Abstract
Novel tetrahydroisoquinoline and tetrahydrobenzazepine compounds of formula (I) capable of modulating the G-protein-coupled receptor GPR120, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as of diabetes, inflammation, obesity and metabolic diseases.