The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Oct. 22, 2020
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Scott D. Larsen, South Lyon, MI (US);
James A. Shayman, Ann Arbor, MI (US);
Kim Hutchings, Dexter, MI (US);
Neil Moss, Ridgefield, CT (US);
Qin Jiang, Latham, NY (US);
Nicholas Mayhew, Niskayuna, NY (US);
Emily Freeman, Voorheesville, NY (US);
Zohreh Sajjadi Hashemi, Frederick, MD (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 205/04 (2006.01); C07D 207/09 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 205/04 (2013.01); C07D 207/09 (2013.01); C07D 405/12 (2013.01);
Abstract
Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.