The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Jun. 19, 2020
Inserm (Institut National DE LA Santé ET DE LA Recherche Mêdicale), Paris, FR;
Baylor Research Institute, Dallas, TX (US);
Universite Paris Est Creteil Val DE Marne, Creteil, FR;
Assistance Publique Hopitaux DE Paris, Paris, FR;
Yves Levy, Paris, FR;
Gerard Zurawski, Midlothian, TX (US);
Sandra Zurawski, Midlothian, TX (US);
Anne-Laure Flamar, New York, NY (US);
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE M{circumflex over (D)}DICALE (INSERM), Paris, FR;
UNIVERSITE PARIS EST CRETEIL VAL DE MARNE, Creteil, FR;
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS, Paris, FR;
BAYLOR RESEARCH INSTITUTE, Dallas, TX (US);
Abstract
Methods and compositions are provided that can be used to vaccinate against and treat HIV. Specifically contemplated are vaccine compositions and methods of using these compositions treat HIV in patients. Aspects of the disclosure relate to an anti-CD40 antibody-HIV antigen fusion protein comprising (i) an anti-CD40 heavy chain (HCD40)-HIV antigen (Ag) fusion protein comprising the formula: HCD40-Ag, wherein Ag is a polypeptide with at least 80% sequence identity to SEQ ID NO:1; and (ii) an anti-CD40 light chain (LCD40).