The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2022

Filed:

Aug. 07, 2015
Applicants:

Haruki Okamura, Osaka, JP;

Kyosuke Yamanishi, Hyogo, JP;

Yoshimasa Tanaka, Nagasaki, JP;

Medical Research and Development Corporation, Aichi, JP;

Foundation for Biomedical Research and Innovation AT Kobe, Hyogo, JP;

Inventors:

Haruki Okamura, Hyogo, JP;

Kyosuke Yamanishi, Hyogo, JP;

Wen Li, Hyogo, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 38/20 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); A61K 38/00 (2013.01); A61K 38/20 (2013.01); A61K 39/395 (2013.01); C07K 16/244 (2013.01); C07K 16/2812 (2013.01); A61K 2039/6056 (2013.01);
Abstract

A cancer therapeutic agent according to an embodiment of the present invention contains, as active ingredients, IL-18 and one or more antibodies selected from the group consisting of an anti-PD-L1 antibody, an anti-PD-1 antibody, an anti-PD-L2 antibody, an anti-CTLA-4 antibody, an anti-CD25 antibody, an anti-CD33 antibody, and an anti-CD52 antibody.


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