The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
May. 10, 2018
Applicant:
Avm Biotechnology, Llc, Seattle, WA (US);
Inventor:
Theresa Deisher, Seattle, WA (US);
Assignee:
AVM Biotechnology, LLC, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/573 (2006.01); A61P 35/00 (2006.01); A61K 35/17 (2015.01); A61K 45/00 (2006.01); A61P 37/00 (2006.01); A61P 31/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/573 (2013.01); A61K 39/0011 (2013.01); A61K 45/00 (2013.01); A61P 31/18 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); A61K 35/17 (2013.01); A61K 2039/515 (2013.01); A61K 2039/5158 (2013.01);
Abstract
Provided herein are novel therapeutic compositions and methods that keep cellular immunotherapies in the circulation or at the site of injection for extended periods of time without resorting to the use of cytotoxic preconditioning. For example, the compositions and methods herein lymphodeplete and reduce or ablate sites in the secondary lymphatics where the cellular immunotherapy is bound and sequestered, without the use of cytotoxic preconditioning.