The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 2022

Filed:

Jun. 13, 2019
Applicants:

Purdue Research Foundation, West Lafayette, IN (US);

Endocyte, Inc., West Lafayette, IN (US);

Inventors:

Christopher Paul Leamon, West Lafayette, IN (US);

Iontcho Radoslavov Vlahov, West Lafayette, IN (US);

Philip Stewart Low, West Lafayette, IN (US);

Assignees:

Endocyte, Inc., West Lafayette, IN (US);

Purdue Research Foundation, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/475 (2006.01); A61K 47/55 (2017.01); A61K 31/517 (2006.01);
U.S. Cl.
CPC ...
A61K 31/475 (2013.01); A61K 31/517 (2013.01); A61K 47/55 (2017.08); A61K 47/551 (2017.08); C07D 487/04 (2013.01);
Abstract

Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.


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