The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Nov. 11, 2016
Applicant:
Ocera Therapeutics, Inc., Palo Alto, CA (US);
Inventors:
Laurene Wang, Chapel Hill, NC (US);
Stanley Bukofzer, Chicago, IL (US);
Linda S. Grais, San Francisco, CA (US);
Assignee:
Ocera Therapeutics, Inc., Hazelwood, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/50 (2006.01); A61K 31/222 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 9/0053 (2013.01); A61K 9/08 (2013.01); A61K 9/5026 (2013.01); A61K 9/5047 (2013.01); A61K 9/5078 (2013.01); A61K 31/222 (2013.01);
Abstract
Some embodiments of the present application are directed to oral formulations of L-ornithine phenylacetate and methods of using the same. These oral formulations offer alternative administration route than the standard intravenous administration of L-ornithine phenylacetate for treating hyperammonemia in patients having various acute and chronic liver diseases and disorders, for example, acute liver failure, liver cirrhosis, liver decompensation, portal hypertension, hepatic encephalopathy, or patients with urea cycle disorders.