The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 11, 2022
Filed:
Nov. 19, 2014
Applicant:
Ohio State Innovation Foundation, Columbus, OH (US);
Inventors:
Ching-Shih Chen, Upper Arlington, OH (US);
Tanios Bekaii-Saab, Upper Arlington, OH (US);
Denis Guttridge, Upper Arlington, OH (US);
Guido Marcucci, Powell, OH (US);
Samuel Kulp, Hiliard, OH (US);
Yu-Chou Tseng, Columbus, OH (US);
Assignee:
OHIO STATE INNOVATION FOUNDATION, Columbus, OH (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01); A61K 31/166 (2006.01); A61K 31/167 (2006.01);
U.S. Cl.
CPC ...
A61K 31/16 (2013.01); A61K 31/166 (2013.01); A61K 31/167 (2013.01);
Abstract
Methods of suppressing cachexia in a mammal with cancer comprising administering HDAC inhibitors are provided. Aspects include methods of administering an HDAC class 1 and 2b inhibitor in an amount effective to substantially maintain the mammal's weight compared to a mammal that does receive the HDAC class 1 and 2b inhibitor.