The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Oct. 07, 2019
Applicant:

National Cheng Kung University, Tainan, TW;

Inventors:

Ping-Ching Wu, Tainan, TW;

Dar-Bin Shieh, Tainan, TW;

Fong-Yu Cheng, Tainan, TW;

Yuh-Ling Chen, Tainan, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/689 (2018.01); A61N 5/06 (2006.01); A61C 1/08 (2006.01); A61C 5/30 (2017.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); A61C 1/088 (2013.01); A61C 5/30 (2017.02); A61N 5/062 (2013.01); A61N 5/0603 (2013.01); A61N 5/0624 (2013.01); A61N 2005/0606 (2013.01); A61N 2005/0659 (2013.01); A61N 2005/0663 (2013.01);
Abstract

Provided herein are aptamers that bind specifically to the surface proteins of periodontal pathogens. Also provided herein are methods for detecting and treating periodontal disease in a subject. The method comprises detecting bacteria associated with periodontal disease by use of the present aptamers to analyze a sample taken from a gum pocket of a tooth of the subject; and treating the periodontal disease of the subject by administering to the gum pocket of the tooth a bactericide or an anti-microbial phototherapy to eradicate the bacteria associated with periodontal disease.


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