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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11214836 B1

PDFFull Text
Date of Patent:
Jan. 04, 2022

Filed:

Jul. 15, 2015

Methods and devices for predicting anthracycline treatment efficacy

Applicant:

Ontario Institute for Cancer Research, Toronto, CA;

Inventors:

Melanie Spears, Etobicoke, CA;

John Bartlett, Toronto, CA;

Fouad Yousif, Burlington, CA;

Paul Boutros, Toronto, CA;

Assignee:

Ontario Institute for Cancer Research, Toronto, CA;

Attorney:

Norton Rose Fulbright US LLP

Primary Examiner:

Sean E Aeder

Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); A61K 31/704 (2006.01); C12M 1/34 (2006.01); C12Q 1/68 (2018.01); G01N 33/574 (2006.01); A61K 38/12 (2006.01); A61K 31/407 (2006.01); A61K 31/136 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/136 (2013.01); A61K 31/407 (2013.01); A61K 31/704 (2013.01); A61K 38/12 (2013.01); C12M 1/34 (2013.01); C12Q 1/68 (2013.01); G01N 33/57415 (2013.01); G01N 33/57484 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention features methods, devices, and kits for predicting the responsiveness of a cancer patient (e.g., a breast cancer patient, such as a grade 1, 2, or 3 breast cancer patient) to anthracycline treatment by determining the expression levels of four chromosomal instability (CIN) genes including HDGF, KIAA0286, RFC4, and MSH6, collectively referred to as CIN4. Patients that have a low CIN4 score benefit from anthracycline treatment compared patients with a high CIN4 score.

Find Patent Forward Citations

Spears, Melanie. (2022). Methods and devices for predicting anthracycline treatment efficacy (U.S. Patent No. 11214836). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11214836

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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