The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Oct. 21, 2019
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Stephen Turner, Eugene, OR (US);

Jon Sorenson, Alameda, CA (US);

Kenneth Mark Maxham, Redwood City, CA (US);

John Eid, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12N 9/12 (2006.01); G16B 30/10 (2019.01); G01N 21/64 (2006.01); G01N 33/487 (2006.01); G16B 30/00 (2019.01); G16B 30/20 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12N 9/1252 (2013.01); G01N 21/6428 (2013.01); G01N 21/6486 (2013.01); G01N 33/48721 (2013.01); G16B 30/10 (2019.02); G01N 2021/6439 (2013.01); G16B 30/00 (2019.02); G16B 30/20 (2019.02);
Abstract

Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.


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