The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Apr. 27, 2018
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Aviv Regev, Cambridge, MA (US);

Brittany Adamson, San Francisco, CA (US);

Brian Cleary, Somerville, MA (US);

Le Cong, Cambridge, MA (US);

Atray Dixit, Cambridge, MA (US);

Jellert Gaublomme, Cambridge, MA (US);

Eric S. Lander, Cambridge, MA (US);

Thomas Norman, San Francisco, CA (US);

Oren Parnas, Jerusalem, IL;

Orit Rozenblatt-Rosen, Sharon, MA (US);

Alexander K. Shalek, Lexington, MA (US);

Jonathan Weissman, San Francisco, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); G16B 5/00 (2019.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); G16B 5/00 (2019.02); C12N 2310/14 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/136 (2013.01);
Abstract

The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.


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