logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11214790 B1

PDFFull Text
Date of Patent:
Jan. 04, 2022

Filed:

Feb. 28, 2017

Hydroxynitrile lyase

Applicant:

Toyama Prefectural University, Toyama, JP;

Inventors:

Yasuhisa Asano, Toyama, JP;

Takuya Yamaguchi, Toyama, JP;

Assignee:

TOYAMA PREFECTURAL UNIVERSITY;

Attorney:

Mendelsohn Dunleavy, P.C.

Primary Examiner:

Richard C Ekstrom

Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12N 9/88 (2006.01); C12N 15/09 (2006.01); C12N 15/10 (2006.01); C12P 13/00 (2006.01); C12N 15/70 (2006.01); C12N 15/85 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1003 (2013.01); C12N 9/88 (2013.01); C12N 15/09 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12N 15/85 (2013.01); C12P 13/00 (2013.01); C12Q 1/6806 (2013.01); C12Q 2600/16 (2013.01); C12Y 401/02047 (2013.01);
Abstract

Provided are a method for obtaining an HNL gene and HNL derived from a millipede other than, and preparing a practically useable amount of HNL; and a method for producing optically active cyanohydrin using this HNL. A method for producing a millipede-derived HNL gene. A method that includes the selection of a gene having a base sequence that encodes a conserved amino acid sequence TAX1DIX2G (SEQ ID NO: 15) or VPNGDKIH (SEQ ID NO: 16) of millipede-derived HNL from genes present in an organism belonging to the Diplopoda. A protein having an amino acid sequence of any of (1)-(3) and having HNL activity. (1) An amino acid sequence listed in any of SEQ ID NOS: 1, 3, 5, 7, 9, 11, 13, 83, 85, 87, or 89; (2) an amino acid sequence having amino acids deleted, substituted, and/or added in an amino acid sequence of (1); or (3) an amino acid sequence having 90% or greater identity to an amino acid sequence of (1). A method for preparing optically active cyanohydrin by causing this millipede-derived HNL to act on a reaction solvent that contains an aldehyde or the like and a substance that generates hydrogen cyanide or the like.

Find Patent Forward Citations

Asano, Yasuhisa. (2022). Hydroxynitrile lyase (U.S. Patent No. 11214790). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11214790

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…