The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Sep. 24, 2015
Applicant:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Tomoyuki Igawa, Shizuoka, JP;

Atsushi Muto, Shizuoka, JP;

Takehisa Kitazawa, Shizuoka, JP;

Tsukasa Suzuki, Shizuoka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2006.01); C07K 16/42 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/36 (2013.01); C07K 16/42 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); C07K 16/00 (2013.01);
Abstract

The present inventors attempted to produce antibodies that neutralize the activity of a substance having an activity of functionally substituting for FVIII to be used for the method of measuring the reactivity of FVIII in the presence of a substance having an activity of functionally substituting for FVIII. As a result, the inventors discovered that by using the produced antibodies, FVIII activity in the plasma of a hemophilia A patient can be evaluated accurately by one-stage clotting assay based on APTT, and also that FVIII inhibitor titer in the plasma of a hemophilia A patient carrying a FVIII inhibitor can be evaluated accurately by Bethesda assay based on APTT.


Find Patent Forward Citations

Igawa, Tomoyuki. (2022). Antibody capable of neutralizing substance having activity alternative to function of coagulation factor viii (fviii) (U.S. Patent No. 11214623). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11214623

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…