The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
Jun. 20, 2017
F-star Delta Limited, Cambridge, GB;
Jamie Campbell, Cambridge, GB;
Nikole Sandy, Cambridge, GB;
Mihriban Tuna, Cambridge, GB;
Francisca Wollerton Van Horck, Cambridge, GB;
Katy Louise Everett, Cambridge, GB;
Miguel Gaspar, Cambridge, GB;
Matthew Kraman, Cambridge, GB;
Katarzyna Kmiecik, Cambridge, GB;
Mustapha Faroudi, Cambridge, GB;
Natalie Fosh, Cambridge, GB;
Barbara Hebeis, Cambridge, GB;
F-star Therapeutics Limited, Cambridge, GB;
Abstract
The present invention relates to antibody molecules which bind to programmed death-ligand 1 (PD-L1) and lymphocyte-activation gene 3 (LAG-3). The antibody molecules preferably comprise a CDR-based antigen binding site for PD-L1, and a LAG-3 antigen binding site which may be located in two or more structural loops of a CH3 domain of the antibody molecule. The antibody molecules of the invention find application, for example, in cancer therapy.