The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Dec. 11, 2019
Applicant:

Glaxosmithkline Biologicals SA, Rixensart, BE;

Inventors:

Stefano Colloca, Rome, IT;

Alfredo Nicosia, Rome, IT;

Riccardo Cortese, Rome, IT;

Virginia Ammendola, S. Guisepe Vesuviano, IT;

Maria Ambrosio, Terzigno, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); C12N 15/861 (2006.01); A61K 39/12 (2006.01); A61K 39/235 (2006.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61K 39/235 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 15/861 (2013.01); A61K 39/0011 (2013.01); A61K 48/00 (2013.01); A61K 2039/525 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/545 (2013.01); C12N 2710/10321 (2013.01); C12N 2710/10322 (2013.01); C12N 2710/10334 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/16634 (2013.01); C12N 2740/16134 (2013.01); C12N 2770/24234 (2013.01);
Abstract

The present invention relates to novel adenovirus strains with an improved seroprevalence. In one aspect, the present invention relates to isolated polypeptides of adenoviral capsid proteins such as hexon, penton and fiber protein and fragments thereof and polynucleotides encoding the same. Also provided is a vector comprising the isolated polynucleotide according to the invention and adenoviruses comprising the isolated polynucleotides or polypeptides according to the invention and a pharmaceutical composition comprising said vector, adenovirus, polypeptide and/or polynucleotide. The invention also relates to the use of the isolated polynucleotides, the isolated polypeptides, the vector, the adenoviruses and/or the pharmaceutical composition for the therapy or prophylaxis of a disease.


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