The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Dec. 20, 2018
Applicant:

Advanced Bionutrition Corp., Columbia, MD (US);

Inventors:

Mordechai Harel, Pikesville, MD (US);

Roger Drewes, Hockessin, DE (US);

Brian Carpenter, Baltimore, MD (US);

Elena Artimovich, Columbia, MD (US);

Assignee:

Advanced BioNutrition Corp., Columbia, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); A61K 9/14 (2006.01); A61K 9/19 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/42 (2017.01); A61K 47/46 (2006.01); C12N 1/04 (2006.01); C12N 11/04 (2006.01); A23L 33/00 (2016.01); A23L 33/135 (2016.01); A23K 40/30 (2016.01); A23K 10/18 (2016.01); A23K 50/42 (2016.01); A61K 9/06 (2006.01); C12N 1/20 (2006.01); A23L 29/00 (2016.01); A23L 33/15 (2016.01); A23K 20/174 (2016.01); A23K 20/189 (2016.01); A23K 50/80 (2016.01);
U.S. Cl.
CPC ...
C07K 14/001 (2013.01); A23K 10/18 (2016.05); A23K 20/174 (2016.05); A23K 20/189 (2016.05); A23K 40/30 (2016.05); A23K 50/42 (2016.05); A23K 50/80 (2016.05); A23L 29/06 (2016.08); A23L 33/135 (2016.08); A23L 33/15 (2016.08); A23L 33/40 (2016.08); A61K 9/06 (2013.01); A61K 9/143 (2013.01); A61K 9/146 (2013.01); A61K 9/19 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 47/42 (2013.01); A61K 47/46 (2013.01); C12N 1/04 (2013.01); C12N 1/20 (2013.01); C12N 11/04 (2013.01); Y02A 40/818 (2018.01);
Abstract

The present invention relates to embedding live or dead microorganisms and/or bioactive materials in a protective dry formulation matrix, wherein the formation includes the bioactive microorganism or material, a formulation stabilizer agent, and a protective agent. The formulation agent is prepared by dispersing all the solid components in a solution, with or without a vacuum, and cooling the solution to a temperature above its freezing temperature. The methods include a primary drying step of the formulation at a desired temperature and time period, and an accelerated secondary drying step under maximum vacuum and elevated temperature, to achieve a final desirable water activity of the dry material.


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