The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Jun. 23, 2017
Applicant:

Konkuk University Industrial Cooperation Corp, Seoul, KR;

Inventors:

Yangmee Kim, Seoul, KR;

Dasom Jeon, Incheon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/05 (2006.01); C07K 7/08 (2006.01); A23K 20/147 (2016.01); A23K 20/195 (2016.01); A23L 33/18 (2016.01); A61K 38/10 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A23K 20/147 (2016.05); A23K 20/195 (2016.05); A23L 33/18 (2016.08); A61K 38/10 (2013.01); A61K 45/06 (2013.01); A23V 2002/00 (2013.01);
Abstract

The present invention relates to an antimicrobial peptide having an improved antibacterial effect through glutamic acid substitution and, more specifically, to a use of the antimicrobial peptide as an active ingredient in an antibacterial pharmaceutical composition, a food additive, a feed additive, an antiseptic composition, and an antibacterial quasi-drug composition. Not only does the antimicrobial peptide of the present invention exhibit significant antibacterial activity against gram-negative bacteria, but it also exhibits a significant synergistic effect when combinedly treated with antibiotics which have strong antibacterial activity only against gram-positive bacteria and has no or low antibacterial activity against gram-negative bacteria, thereby exhibiting excellent antibacterial effects on gram-positive bacteria,andbacteria among gram-negative bacteria, and antibiotic-resistant strains thereof.


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