The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
Oct. 18, 2019
California Institute of Technology, Pasadena, CA (US);
Brian M. Stoltz, San Marino, CA (US);
Alexander W. Sun, Irvine, CA (US);
Stephan N. Hess, Pasadena, CA (US);
Carina I. Jette, Pasadena, CA (US);
Irina Geibel, Bad Zwischenahn, DE;
Shoshana Bachman, Las Vegas, NV (US);
Masaki Hayashi, Kanagawa, JP;
Hideki Shimizu, Hyogo, JP;
Jeremy B. Morgan, Wilmington, NC (US);
Shunya Sakurai, Kyoto, JP;
Zachary P. Sercel, Pasadena, CA (US);
California Institute of Technology, Pasadena, CA (US);
Abstract
Described here are transition metal-catalyzed enantioselective arylation and vinylation reactions of α-substituted lactams, such as γ-lactams. The use of various electrophiles and ligands are described, and result in the construction of α-quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee).