The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
May. 15, 2018
Applicant:
Cognition Therapeutics, Inc., Pittsburgh, PA (US);
Inventors:
Gilbert M. Rishton, Los Angeles, CA (US);
Gary C. Look, Santa Clara, CA (US);
Susan M. Catalano, Pittsburgh, PA (US);
Assignee:
Cognition Therapeutics, Inc., Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/107 (2006.01); C07D 205/04 (2006.01); C07D 207/08 (2006.01); C07D 207/16 (2006.01); C07D 211/22 (2006.01); C07D 211/46 (2006.01); C07D 211/48 (2006.01); C07D 241/04 (2006.01); C07D 241/08 (2006.01); C07D 265/30 (2006.01); C07D 401/04 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 205/04 (2013.01); C07D 207/08 (2013.01); C07D 207/16 (2013.01); C07D 211/22 (2013.01); C07D 211/46 (2013.01); C07D 211/48 (2013.01); C07D 241/04 (2013.01); C07D 241/08 (2013.01); C07D 265/30 (2013.01); C07D 401/04 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 413/14 (2013.01); C07D 491/107 (2013.01);
Abstract
The present disclosure relates to novel compounds, and pharmaceutical compositions thereof, useful for treating for treating neurodegenerative diseases, including Alzheimer's disease and cognitive decline. Methods for inhibiting synapse number decline or membrane trafficking abnormalities associated with exposure of a neuronal cell to Abeta species are also disclosed. Representative members of these compounds include: