The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
May. 16, 2018
Wisconsin Alumni Research Foundation, Madison, WI (US);
University of Leiden, Leiden, NL;
University of Chicago, Chicago, IL (US);
David Charles Schwartz, Madison, WI (US);
Kristy L. Kounovsky-Shafer, Kearney, NE (US);
Juan Pablo Hernandez-Ortiz, Madison, WI (US);
Konstantinos Dimitrios Potamousis, Madison, WI (US);
Juan Jose De Pablo, Chicago, IL (US);
Theo Odijk, Leiden, NL;
Kyubong Jo, Seoul, KR;
Wisconsin Alumni Research Foundation, Madison, WI (US);
University of Leiden, Leiden, NL;
University of Chicago, Chicago, IL (US);
Abstract
Devices, systems, and methods for en masse patterning of nucleic acid molecule structures are disclosed. The devices can include microchannels and nanoslits. The microchannels and nanoslits can be connected by parking chambers. The systems and methods can utilize the geometry of the devices in coordination with a voltage application routine to park nucleic acid molecules in the parking chambers and subsequently inject the nucleic acid molecules into the nanoslits. The methods can be utilized to present nucleic acid molecules in a fashion suitable for genomic analysis. The methods can also be utilized to provide size selection of the nucleic acid molecules.