The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
Mar. 20, 2018
Applicant:
The George Washington University, Washington, DC (US);
Inventors:
Assignee:
The George Washington University, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/54 (2006.01); A61L 27/52 (2006.01); A61K 35/51 (2015.01); A61K 35/28 (2015.01); A61K 38/18 (2006.01); A61F 2/28 (2006.01); A61F 2/30 (2006.01); A61L 27/26 (2006.01); A61L 27/18 (2006.01); A61L 27/34 (2006.01); A61L 27/38 (2006.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01); B33Y 80/00 (2015.01);
U.S. Cl.
CPC ...
A61L 27/54 (2013.01); A61F 2/28 (2013.01); A61F 2/3094 (2013.01); A61F 2/30771 (2013.01); A61K 35/28 (2013.01); A61K 35/51 (2013.01); A61K 38/1866 (2013.01); A61K 38/1875 (2013.01); A61L 27/18 (2013.01); A61L 27/26 (2013.01); A61L 27/34 (2013.01); A61L 27/3808 (2013.01); A61L 27/3834 (2013.01); A61L 27/3886 (2013.01); A61L 27/52 (2013.01); B33Y 10/00 (2014.12); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12); A61F 2002/2817 (2013.01); A61F 2002/30014 (2013.01); A61F 2002/30062 (2013.01); A61F 2002/3092 (2013.01); A61F 2002/30327 (2013.01); A61F 2002/30677 (2013.01); A61F 2002/30784 (2013.01); A61F 2002/30985 (2013.01); A61F 2310/0097 (2013.01); A61F 2310/00976 (2013.01); A61L 2300/414 (2013.01); A61L 2430/02 (2013.01); A61L 2430/40 (2013.01);
Abstract
Biphasic tissue constructs that include a scaffold having one or more channels, a vascular portion comprising a hydrogel at least partially disposed in the one or more channels, and a first bioactive growth factor and a second bioactive growth factor different from the first bioactive growth factor, the first bioactive growth factor localized to the scaffold and the second bioactive growth factor localized to the vascular portion. The first bioactive growth factor may be bone morphogenetic protein 2 (BMP2) peptide and the second bioactive growth factor may be vascular endothelial growth factor (VEGF) peptide.