The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
Nov. 03, 2015
Applicant:
Thrombolytic Science, Llc, Cambridge, MA (US);
Inventor:
Victor Gurewich, Cambridge, MA (US);
Assignee:
Thrombolytic Science, LLC, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/49 (2006.01); A61K 38/57 (2006.01); A61P 9/10 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/49 (2013.01); A61K 9/0019 (2013.01); A61K 38/57 (2013.01); A61P 9/10 (2018.01); C12Y 304/21068 (2013.01); C12Y 304/21073 (2013.01);
Abstract
Provided herein are methods for safe and effective thrombolysis in therapy for human subjects with symptoms of a potential stroke or acute myocardial infarction ('AMI') using a sequential administration of a low dose bolus of human tissue plasminogen activator ('tPA') followed by an infusion of a mutant form of human pro-urokinase (“proUK”).