The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 04, 2022

Filed:

Apr. 17, 2017
Applicants:

University of South Florida, Tampa, FL (US);

Uab Research Foundation, Birmingham, AL (US);

Inventors:

Bill J. Baker, Tampa, FL (US);

Lindsey N. Shaw, Tampa, FL (US);

James Bruce McClintock, Birmingham, AL (US);

Charles D. Amsler, Pelham, AL (US);

Jacqueline Lee Fries, Sarasota, FL (US);

Witowski G. Christopher, Sarasota, FL (US);

Renee M. Fleeman, Tampa, FL (US);

Assignees:

UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);

UAB RESEARCH FOUNDATION, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/365 (2006.01); A61P 31/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/365 (2013.01); A61K 9/0014 (2013.01); A61P 31/04 (2018.01); C07B 2200/13 (2013.01);
Abstract

Provided is a darwinolide compound having a previously undescribed carbon skeleton and the crystalline form thereof. Also provided are processes of isolating darwinolide, compositions comprising darwinolide, and methods of treating infection, such as a methicillin-resistantbiofilm infection.


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