The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 04, 2022
Filed:
Aug. 26, 2020
Secretary, Department of Atomic Energy, Mumbai, IN;
Amit Kunwar, Mumbai, IN;
Vishwa Vipulkumar Gandhi, Mumbai, IN;
Khushboo Atulkumar Gandhi, Mumbai, IN;
Vikram Suryaprakash Gota, Mumbai, IN;
Jayant Sastri Goda, Mumbai, IN;
Jyoti Anand Kode, Mumbai, IN;
Liladhar Baburao Kumbhare, Mumbai, IN;
Vimal Kumar Jain, Mumbai, IN;
Kavirayani Indira Priyadarsini, Mumbai, IN;
Secretary, Department of Atomic Energy, Mumbai, IN;
Abstract
The present invention describes the method of using a synthetic organoselenium compound, DSePA for management of non-small cell lung carcinoma (NSCLC) and chronic myelogenous leukemia (CML). The method comprises administering DSePA orally at a dosage of 1 mg/Kg body weight daily for inhibiting the growth of A549 (representative of NSCLC) and K562 (representative of CML) tumor in mice models. Additionally, the said compound also inhibits the proliferation of other cancer cells of NSCLC (HOP-62 and H460), breast (MDA-MB-231), white blood cells (JURKAT and U-937), oral (SCC-40), colon (HT-29), kidney (A498) and cervix (SiHA) origins in cellular models at a much lower concentration than that needed to inhibit the growth of normal cells.