IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11213496 B1

PDFFull Text
Date of Patent:
Jan. 04, 2022

Filed:

Sep. 10, 2018

Methods of using dipivefrin

Applicant:

Insignis Therapeutics, Inc., North Haven, CT (US);

Inventor:

Mingbao Zhang, Millwood, NY (US);

Assignee:

INSIGNIS THERAPEUTICS, INC., North Haven, CT (US);

Attorney:

Cantor Colburn LLP

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Ibrahim D Bori

Int. Cl.
CPC ...
A61K 31/37 (2006.01); A61K 9/00 (2006.01); A61K 47/38 (2006.01); A61K 47/42 (2017.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 11/16 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 37/08 (2006.01); A61K 31/222 (2006.01); A61P 31/16 (2006.01); A61K 31/137 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 9/0056 (2013.01); A61K 47/38 (2013.01); A61K 47/42 (2013.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); A61P 11/16 (2018.01); A61P 31/00 (2018.01); A61P 31/04 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); A61P 37/08 (2018.01);
Abstract

The disclosure provides a method for systemic delivery of a therapeutically effective amount of epinephrine to a subject comprising orally administering dipivefrin or a dipivefrin salt to the subject. The disclosure also includes a method of treatment of a disease amenable to treatment by in vivo delivery of systemic epinephrine comprising administering dipivefrin or a dipivefrin salt to a subject in need of in vivo delivery of systemic epinephrine. The disease can be a respiratory disorder, anaphylaxis, cancer, or a microbial infection. The disclosure also includes dipivefrin or dipivefrin HCl orally dissolving tablets.

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