The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Mar. 26, 2018
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Daniel T. Kamei, Monterey Park, CA (US);

Maie A. ST John, Los Angeles, CA (US);

Zachary D. Taylor, Los Angeles, CA (US);

Daniel W. Bradbury, Los Angeles, CA (US);

Ashley E. Kita, Los Angeles, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); G01N 33/48 (2006.01); H04M 1/725 (2021.01);
U.S. Cl.
CPC ...
G01N 33/54386 (2013.01); B01L 3/5023 (2013.01); B01L 2400/0406 (2013.01); G01N 2333/99 (2013.01);
Abstract

Devices and methods are provided for the detection of CSF in a biological sample. In certain embodiments the device is a lateral flow device comprising: a porous substrate; a sample addition zone disposed on or in said porous substrate; a detection zone disposed on or in said porous substrate where said detection zone comprises at least a first test line (T) and a second test line (T) each test line comprising binding moieties that bind a complex formed between beta-trace protein (betaTP) and an indicator attached to a betaTP binding molecule; wherein said porous substrate defines a flow path through which a sample applied to the sample addition zone flows under capillary action away from said sample addition zone into said detection zone.


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