The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2021
Filed:
Jul. 19, 2019
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventor:
Bin Liu, San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); G01N 33/574 (2006.01); A61K 51/10 (2006.01); C07K 16/30 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 47/6803 (2017.08); A61K 47/6811 (2017.08); A61K 47/6829 (2017.08); A61K 47/6849 (2017.08); A61K 47/6869 (2017.08); A61K 51/1072 (2013.01); A61K 51/1093 (2013.01); A61K 51/1096 (2013.01); C07K 16/3069 (2013.01); G01N 33/57434 (2013.01); G01N 33/57492 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/77 (2013.01); G01N 2333/70596 (2013.01);
Abstract
In various embodiments various cancer specific antibodies and immunoconjugates are provided. In certain embodiments the antibodies specifically bind and are internalized into a prostate cancer cell, where the antibodies specifically binds cells that express or overexpress a CD46, and where the antibodies specifically bind sushi domain 1 of said CD46 (CD46 CPP1).