The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Feb. 12, 2018
Applicant:

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Jerusalem, IL;

Inventors:

Rachel Nechushtai, Motza I'llit, IL;

Assaf Friedler, Mevaseret Zion, IL;

Anat Iosub-Amir, Jerusalem, IL;

Merav Darash-Yahana, Jerusalem, IL;

Yang-Sung Sohn, Modi'in, IL;

Dorit Michaeli, Mevaseret Zion, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/17 (2006.01); A61K 47/60 (2017.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A61K 38/1709 (2013.01); A61K 45/06 (2013.01); A61K 47/60 (2017.08); A61P 35/00 (2018.01); A61K 38/00 (2013.01);
Abstract

The present invention provides peptides comprising a sequence derived from the human NAF-1 protein, analogs of said sequence or a retro-inverso sequence of said peptide or analog. The conjugates of such peptides are provided as well. The peptides and the conjugates of the present invention are useful in treating cancer, and in particular cancer in which the expression of NAF-1 is enhanced.


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