The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 2021

Filed:

Jul. 06, 2020
Applicants:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Inventors:

Aravind Asokan, Chapel Hill, NC (US);

Mavis Agbandje-McKenna, Gainesville, FL (US);

Long Ping Victor Tse, Carrboro, NC (US);

Brittney Gurda, Collegeville, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C07K 16/08 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C07K 16/081 (2013.01); C12N 15/86 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C12N 2750/14122 (2013.01); C12N 2750/14143 (2013.01); C12N 2810/6027 (2013.01);
Abstract

The present invention provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The invention also provides methods of administering the virus vectors and virus capsids of the invention to a cell or to a subject in vivo.


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