The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 28, 2021
Filed:
Jun. 14, 2018
Applicant:
Eisai R&d Management Co., Ltd., Tokyo, JP;
Inventors:
Yoshinori Takahashi, Ibaraki, JP;
Yuta Suzuki, Ibaraki, JP;
Assignee:
Eisai R&D Management Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07D 239/54 (2006.01); C07D 239/47 (2006.01); C07D 473/34 (2006.01); C07D 473/18 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C07D 239/47 (2013.01); C07D 239/54 (2013.01); C07D 473/18 (2013.01); C07D 473/34 (2013.01); C07H 21/04 (2013.01);
Abstract
The present invention provides a modified nucleic acid monomer compound having a specific backbone such as 2-ethylglycerol or methoxymethyl-1,3-propanediol backbone instead of a ribose or deoxyribose backbone of a nucleoside, and an oligonucleic acid analogue containing the monomer compound as at least one of building blocks. The oligonucleic acid analogue containing the nucleic acid monomer compound of the present invention allows provision of an oligonucleic acid analogue having excellent biological stability and/or target gene silencing activity.